ABSTRACT
Objective To evaluate the clinical value of transcranial Doppler (TCD) on the measurement of cerebral arterio-venous pulse wave time (CAV-PWT). Methods 86 patients with ischemic cerebrovascular disease (ICD) were received by TCD and digital subtraction angiography (DSA). The relationship of CAV-PWT and the stenosis degree of intracerebral arteries (IA) was evaluated by linear correlation analysis. Follow-up was made for half year, and the cases of cerebral stroke were recorded. The risk of CAV-PWT and cerebral stroke was evaluated by multivariate Logistic regression analysis. Results There were no difference on the stenosis rate of intracervical artery system and vertebrobasilar artery system by DSA or TCD, which were 52.33% vs 47.86%(P = 0.056) and 61.63% vs 56.98%(P = 0.059). The positive relationship of CAV-PWT and mean arterial pressure to the stenosis degree of IA was confirmed by linear correlation analysis (r = 0.832,P = 0.025 and r =0.625,P = 0.040). The CAV-PWT was the independent risk factor in the occurrence of cerebral stroke by multivariate Logistic regression analysis (OR = 1.527). Conclusion The CAV-PWT detected by TCD can evaluate the stenosis degree of IA and also has perfect clinical value to patients′ prognosis.